food allergy
Conditions
Interventions
the consumption of 600mg/day fermanted soy product from 1~2 month before ROIT to 3 months after the end of rash phase of OIT
the consumption of plasebo from 1~2 month before starting ROIT until 3 mont
Sponsors
Aichi Children's Health and Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: patient with severe food allergy for egg, milk, wheat diagnosed by oral food challenge
Exclusion criteria
Exclusion criteria: patients with severe comorbidity patients with uncontrollable asthma or atopic dermatitis patients with severe food allergy for soybeans patients whom the doctor assess ineligible
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The total score of allergic reaction score plus rescue drug score during rash phase of OIT. | — |
Secondary
| Measure | Time frame |
|---|---|
| The amount of food consumption and the proportion of patients who reached the target dose (20g of boiled egg, 100ml of milk and 100g of udon noodle) at discharge and at 3 months after discharge. The changes in value of laboratory data (e.g. specific IgE titer) The changes in value of the threshold dose of antigen and severity of allergic reaction provoked in OFCs | — |
Countries
Japan
Contacts
Public ContactIwao Tajima
Aichi Children's Health and Medical Center Department of Allergy
Outcome results
None listed