N/A (healthy adults)
Conditions
Interventions
[1]Oral intake of the test product (1 day,1 time) [2]The exposure to cold water stress [3]Observation [4]Washout (2 week) [5]Oral intake of the placebo product (1 day,1 time) [6]The exposure
Sponsors
Anti-Aging Bank Co.,Ltd.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: [1]Japanese females after menopause aged 45-65 years [2]Individuals who are healthy and do not treat any disease [3]Individuals with objective feeling chillness and individual who can admit that it's a chillness objectively in a chillness questionnaire [4]Individuals whose written informed consent has been obtained [5]Individuals who can have an examination on a designated check day [6]Individuals judged appropriate for the study by the principal
Exclusion criteria
Exclusion criteria: [1]Individuals using medical products [2]Individuals who are or are under treatment or have a history of mental disabilities,sleep disorder,hypertension,diabetes,fat metabolism or the other serious dysfunctions [3]Individuals who used a drug to treat in the past 1 month (One-shot medicine of a headache, menstrual pain and a cold removes it.)[4]Individuals who have a history of serious hepatopathy, kidney damage, heart disease, lung disease,or blood disease [5]Individual who have digestive organ disease(disease of an appendix is removed) [6]Individuals whose BMI is over 30 kg/m2 [7]Individuals who donated blood over 200mL in the past 1 month or over 400mL in the past 3 months [8]Individuals with serious anemia [9]Individuals who are sensitive to test products or Individual with fear who causes severe allergy in a food and medical supplies [10]Individual who is based on average alcohol per 1 day and exceeds 60g/day [11]Individuals whose life style will change during the test period (ex. travel for a long time) [12]Individuals who had a habit to ingest health-promoting foods, foods for specified health uses, health foods, or supplyments in the past 3 months or will ingest those foods during the test period [13]Individuals whose SMI score is over 51 [14]Individuals who have a history of ovarian resection or hysterectomy [15]Individuals who participated in other clinical studies in the past 3 months [16]Individuals judged inappropriate for the study by the principal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| [1]Blood flow (Preliminary observation, First bbservation, Second observation) [2]Skin surface temperature (Preliminary observation, First bbservation, Second observation) | — |
Secondary
| Measure | Time frame |
|---|---|
| [1]Subjective questionnaire (Preliminary observation, First bbservation, Second observation) [2]Physician's interview (Preliminary observation, First bbservation, Second observation) | — |
Countries
Japan
Contacts
Public ContactToshiyasu Tamura
TES Holdings Co., Ltd. Department of Clinical Trial
Outcome results
None listed