Pediatric patients who are scheduled for living donor liver transplantation
Conditions
Interventions
Anesthetic management with Desflurane
Anesthetic management with Sevoflurane
Sponsors
National Center for Child Health and Development
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) patients who are scheduled for living donor liver transplantation at National Center for Child Health and Development, Tokyo, Japan; 2) patients weighted more than or equal to 6kg; 3) patients aged less than 16 years old; 4) patients whose informed consent is obtained from their guardians before operation
Exclusion criteria
Exclusion criteria: 1) preoperative ICU management; 2) other organ complications caused by diseases other than the present liver illness; 3) allergy to either/both of inhalation anesthetic(s) or halogenated agents; 4) past history of malignant hyperthermia or family history of malignant hyperthermia; 5) metabolic disease; 6) acute liver failure; 7) pulmonary hypertension; 8) respiratory tract symptoms within 2 weeks before surgery; 9) asthma; 10) any cases inappropriate for the trial judged by surgeons or anesthesiologists in charge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ratio of operating room extubation after pediatric living donor liver transplantation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Length of postoperative intubation 2) Length of Intensive care unit stay 3) Perioperative blood examination 4) Perioperative vital sign change 5) Perioperative infusion therapy volume 6) Perioperative urine output change 7) Ratio of postoperaitve infection 8) Ratio of postoperative rejection | — |
Countries
Japan
Contacts
Public ContactChiaki Baba
National Center for Child Health and Development Anesthesia and ICU
Outcome results
None listed