Nothing (healthy subjects)
Conditions
Interventions
Intake test diet (product code: A-001) for 28 days (one serving size per day) >
wash out more than 28 days >
intake control diet (product code: C-001) for 28 days (one serving size per day)
Intake control diet (product code: C-001) for 28 days (one serving size per day) >
intake test diet (product code: A-001) for 28 days (one serving size per day)
Sponsors
Kao Corporation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Age>=35 and <65 years 2.BMI>=23 and < 30 kg/m2 3.Person who provides informed consent by a document.
Exclusion criteria
Exclusion criteria: 1.Person who is difficult to participate the study due to presence of liver, kidney, and heart disease; respiratory, endocrine, metabolic, nervous system, or cognitive disorders; or diabetes or other diseases. 2.Person who has skin infection or dysfunction on abdominal. 3.Person who has constipation more than 5 days. 4.Person whose waist circumference is less than 55 cm or more than 140 cm. 5.Person who has surgical or treatment history for disease or injury within two months before the trial. (except for common cold, abdominal pain, allergic rhinitis) 6.Person who taking medicine for hyperglycaemia, lipid metabolism, or hypertension. 7.Person who experienced unpleasant feeling during drawing blood. 8.Person who has donated 200 mL or more blood within one month before the trial. 9.Person who has possibility for allergies to ingredients in the test food or equipment used for indirect calorimetry. 10.Person whose weight changes more than +-5 kg within one month before the trial. 11.Person who is shift worker. 12.Person who planned business trip lasting 5 consecutive days or more. 13.Person who habitually takes the FOSHU (foods for specified health uses), functional food, or dietary supplements affecting current study (e.g. serum cholesterol, serum triglyceride, fat weight, blood glucose). (Except for person who can stop consume them after informed consent). 14.Person who inability or unwillingness to conform to the alcohol limitation (more than 30 g/day alcohol). 15.Person who inability or unwillingness to record diary during current study. 16.Person who inability or unwillingness to record daily diet during current study. 17.Person who is smoker. 18.Person who participating or planning to participate in other clinical studies. 19.Person who can't agree current informed consent. 20.Person who determined to be unqualified by the supervising physician based on the medical record or other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dietary fat oxidation after 28 days repeated ingestion (breath analysis data) | — |
Secondary
| Measure | Time frame |
|---|---|
| Basal metabolic rate, Postprandial energy expenditure, Postprandial total fat oxidation, Postprandial respiratory quotient. | — |
Countries
Japan
Contacts
Public ContactShinpei Tomita
New drug research center Co. Ltd Research Division
Outcome results
None listed