Analyses of the clinicopathological significance of cancer-stromal interaction factors expressed in the esophageal cancer tissues

Analyses of the clinicopathological significance of cancer-stromal interaction factors expressed in the esophageal cancer tissues - Analyses of the clinicopathological significance of cancer-stromal interaction factors expressed in the esophageal cancer tissues

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000022713

Enrollment

300

Registered

2016-07-15

Start date

2016-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Approximately 300 surgically resected esophageal cancer patients at the National Cancer Center Hospital East during the period from 2000 January 1 to 2011 December 31, whom paraffin-embedded blocks of tissue microarray specimens were stored in the National Cancer Center Exploratory Oncology Research and Clinical Trial Center

Exclusion criteria

Exclusion criteria: Whom specimens can not be used for analysis during the sample preparation of the tissue microarray specimens

Design outcomes

Primary

Measure	Time frame
Post-operative recurrence-free survival and overall survival	—

Secondary

Measure	Time frame
Items collected from cancer tissue by image analysis, specifically, morphometric parameters such as macrophage density in cancer tissue, macrophage major axis, minor axis, area, average cytoplasmic aspect ratio, cytoplasmic content of target protein Mean fluorescence intensity, sum of cytoplasmic fluorescence intensity	—

Countries

Japan

Contacts

Public ContactMari Nishio

Kobe University Graduate School of Medicine Division of Pathology, Department of Pathology

marin@med.kobe-u.ac.jp078-382-5465

Outcome results