normal subject
Conditions
Interventions
Skin biopsy,blood collection,stratum corneum collection
Sponsors
Asahikawa Medical University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1.Japanese females over 20 years old at the informed consent. 2.Patients who understand in detail and have written consent for the study protocol.
Exclusion criteria
Exclusion criteria: 1.Patients suffering from atopic dermatitis, psoriasis or netherton syndrome. 2.Patients having a severe sunburn within 2 weeks before the test. 3.Patients taking hormonal replacement therapy. 4.Patients taking chemical peeling and laser therapy, and using drugs such as hydroquinone, vitamin C, retinoic acid which were prescribed by a doctor within 3 month before the test. 5.Women who are pregnant, may be pregnant or breastfeeding. 6.Patients who are judged inappropriate to participate by investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Evaluation of the disruption of KLK7 in skin using immunohistochemistry. 2.Evaluation of expressed level of KLK7 in stratum corneum. 3.Evaluation of expressed level of KLK7 in blood. | — |
Countries
Japan
Contacts
Public ContactSatomi Igawa
Asahikawa Medical University Dermatology
Outcome results
None listed