The Clinical Efficacy of Carbonic Anhydrase Inhibitors and Steroids in the Management of Cystoid Macular Edema in Patients with Retinitis Pigmentosa

The Clinical Efficacy of Carbonic Anhydrase Inhibitors and Steroids in the Management of Cystoid Macular Edema in Patients with Retinitis Pigmentosa - The Clinical Efficacy in the Management of Cystoid Macular Edema in Patients with Retinitis Pigmentosa

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022686

Enrollment

Registered

2016-07-01

Start date

2016-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

retinitis pigmentosa

Interventions

1% dorzolamide eye drop three times daily in each eye 0.1% betamethasone sodium phosphate eye drop three times daily in each eye oral 250mg acetazolamide two tablets daily 40mg triamcinolone aceto

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) patients with retinitis pigmentosa (2) BCVA >= 0.1 (3) patinets whose agreement was shown by him/herself

Exclusion criteria

Exclusion criteria: (1) a past history of glaucoma or intraocular hypertension (2) patients with another macular disorder, such as epiretinal membrane (3) a past history of using the test drug within 6 months (4) pregnant subjects, subjects suspected of being pregnant, or breast-feeding subjects (5) patients with steroid induced intraocular hypertension (6) hypersensitivity to these test drugs (7) a past history of the entry into another clinical trial within 1 year (8) inappropriate case judged by investigator or subinvestigators

Design outcomes

Primary

Measure	Time frame
retinal thickness	—

Secondary

Measure	Time frame
best-corrected visual acuity, visual field, side effect	—

Countries

Japan

Contacts

Public ContactYasuhiro Ikeda

Kyushu University Hospital Department of Ophthalmology

ymocl@pathol1.med.kyushu-u.ac.jp092-642-5648

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026