Mean kurtosis alterations of cerebral white matter in patients with schizophrenia revealed by diffusion kurtosis imaging

Mean kurtosis alterations of cerebral white matter in patients with schizophrenia revealed by diffusion kurtosis imaging - MK alterations of cerebral WM in patients with schizophrenia revealed by diffusion kurtosis imaging

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000022670

Enrollment

Registered

2016-06-10

Start date

2013-06-19

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: schizophrenia was diagnosed by a research psychiatrist ( H.N. 8 years of experience in psychiatry) based on the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) using the Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I).

Exclusion criteria

Exclusion criteria: any absolute contraindication to MRI, comorbidity of axis I or II disorders, history of diseases that might affect WM integrity (i.e., prior head injury, cerebrovascular disorder, or degenerative disease), existence of past substance abuse or dependency, pregnancy, or a high risk of suicide.

Design outcomes

Primary

Measure	Time frame
Alteration of MK and FA values.	—

Countries

Japan

Contacts

Public ContactHisashi Narita

Hokkaido University Graduate School of Medicine Dept. of Psychiatry

aqualife99@hotmail.com0117065160

Outcome results