Elective surgical patients
Conditions
Interventions
Initial dose of rocuronium: 0.6 mg/kg, Maintenance of anesthesia: propofol.
Initial dose of rocuronium: 0.6 mg/kg, Maintenance of anesthesia: desflurane.
Initial dose of rocuronium: 0.6 mg/kg, Mainten
Sponsors
Jikei University School of Medicine, Department of Anesthesiology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Acquisition of written informed consent. 2. Elective surgical patients. 3. Age; 20 years old or more and less than 65 years old. 4. Duration of anesthesia; 1.5 to 5 hours.
Exclusion criteria
Exclusion criteria: 1. American Society of Anesthesiologists criteria; 3 or more. 2. Pregnant patients. 3. Body mass index; 30 kg/m2 or more. 4. Body mass index; less than 18.5 kg/m2. 5. Severe renal dysfunction patients; serum creatinine exceeded reference value. 6. Hepatic dysfunction patients; serum transaminase more than 100 U/L. 7. Patients with metabolic disorder. 8. Patients with neuromuscular disorder. 9. Patients with dyspnea, airway stenosis, and/or bronchial asthma. 10. Patients with hypersensitivity for rocuronium or sugammadex. 11. Patients with atopic disease. 12. Patients with systemic allergic symptoms. 13. Taking antihistamine and/or antiallergic drugs for more than a month. 14. Taking calcium antagonists, anticonvulsant agents, aminoglycoside antibiotics, polypeptide antibiotics, and/or metronidazole. 15. Patients required management with hypothermia during surgery. 16. Difficulty with appropriate neuromuscular monitoring. 17. Emergency surgical patients. 18. Patients with life-threatening medical condition.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Infusion rate of rocuronium to maintain the neuromuscular blockade at 1 to 5 of post tetanic count at adductor pollicis. | — |
Countries
Japan
Contacts
Public ContactHiroshi Sunaga
Jikei University School of Medicine Department of Anesthesiology
Outcome results
None listed