Study on inhibitory effect of teriparatide in knee osteoarthritis

Study on inhibitory effect of teriparatide in knee osteoarthritis - Inhibitory effect of teriparatide in knee osteoarthritis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022598

Enrollment

Registered

2016-08-01

Start date

2016-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

teriparatide VitaminD

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Primary ssteoprosis Knee osteoarthritis with Kellgren-Lawrence grade 2 or 3 Patients with knee joint pain History without treatment of osteoprosis, including hormone therapy, SERM,Bisphosfonate, teriparatide, anti RANKL antibody, eldecarcitol

Exclusion criteria

Exclusion criteria: Usage of glucocorticoide Severe of knee osteoarthritis and deformity Lower pain caused by lumber spine History of knee joint surgery Patient to lack in ability to know informed consent Dementia Contraindication to use teriparatide Inadequate patient judged by doctors

Design outcomes

Primary

Measure	Time frame
Change of joint space narrowing and bone trabecular integrity using plain X ray of knee joint at 2 years	—

Secondary

Measure	Time frame
MRI of knee joint, kL grade using plain X ray of knee joint, WOMAC score,and Knee society score at 2 years	—

Countries

Japan

Contacts

Public ContactMoritoshi Furu

Kyoto University Hospital Center for Rheumatic diseases

morifuru@kuhp.kyoto-u.ac.jp0757513877

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026