The efficacy of automated intermittent thoracic paravertebral bolus technique for analgesia after thoracotomies: prospective, randomized, controlled, double-blind study

The efficacy of automated intermittent thoracic paravertebral bolus technique for analgesia after thoracotomies: prospective, randomized, controlled, double-blind study - The efficacy of automated intermittent thoracic paravertebral bolus technique for analgesia after thoracotomies: prospective, randomized, controlled, double-blind study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022532

Enrollment

Registered

2016-05-30

Start date

2016-05-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult patients scheduled for elective unilateral thoracotomy (lung lobectomy or pulmonary segmentectomy) under combination of general anesthesia and thoracic paravertebral block

Interventions

Postoperative continuous thoracic paravertebral infusion of 0.2% levobupivacaine at 5 ml/h for 48 h Postoperative automated intermittent thoracic paravertebral bolus of 0.2% levobupivacaine 10 ml ever

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Patients undergoing elective unilateral lung lobectomy or pulmonary segmentectomy at Nagasaki University Hospital 2.American Society of Anesthesiologists Physical Status Classification I-III 3.Patients signed the informed consent form

Exclusion criteria

Exclusion criteria: 1.Age < 20 or > 80 years 2.Prior thoracotomy on ipsilateral side 3.Body mass index > 30 kg/m2 4.Body weight < 40 kg 5.Allergy to local anesthetics 6.Contraindication to non-steroidal anti-inflammatory drugs, fentanyl, iodinated contrast medium 7.Hepatic or renal failure 8.Chronic opioid use 9.Pre-existing neurological deficit 10.Infection at the site of injection 11.Bronchial asthma 12.Inability to communicate lucidly

Design outcomes

Primary

Measure	Time frame
Anesthetized dermatomes by thoracic paravertebral block 24 h after surgery	—

Countries

Japan

Contacts

Public ContactHiroaki Murata

Nagasaki University Graduate School of Biomedical Sciences Department of Anesthesiology

h-murata@nagasaki-u.ac.jp095-819-7370

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026