Prospective study of delayed bleeding after colorectal EMR and polypectomy in patients receiving Rivaroxaban uninterruptedly before retiring

Prospective study of delayed bleeding after colorectal EMR and polypectomy in patients receiving Rivaroxaban uninterruptedly before retiring - Prospective study of delayed bleeding after colorectal EMR and polypectomy in patients receiving Rivaroxaban uninterruptedly before retiring(RUBR)

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022519

Enrollment

Registered

2016-05-31

Start date

2016-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal polyps

Interventions

Before the admission of the colorectal polypectomy about 2 weeks,patients start to take a 15mg tablet of Rivaroxaban before retiring. Reducing criteria for 10mg Rivaroxaban Ccr less than50ml/mi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients receiving anticoagulants with colorectal polyps under 20mm diameter Performance status 0 or 1 WBC over3000/mm3 and under12000/mm3 Hb over9.0g/dL Plt over100000/mm3 AST,ALT under100IU T.Bil under2.0mg/dL Ccr less than1.77mg/dL and Ccr over15ml/min PT-INR under3 (less than70 years old) PT-INR under2.6(over70 years old)

Exclusion criteria

Exclusion criteria: Contraindicated cases for taking Rivaroxaban Patients with artifical heart valve Patients with vasucular atrial fibrillation Liver chirrhosis patients with type B or C in child-pugh classfication Patients taking azole antifungal drug,the HIV-protease inhihibitors or drugs including cobicistat Patinens contracting acute infective endocarditis Women who are or may be pregnant Patients taking aspirin or Thienopyridine Dialysis patients Patients with past history of gastrointestinal bleeding or intracranial hemorrhage

Design outcomes

Primary

Measure	Time frame
analysis of delayed bleeding after colorectal polypectomy and EMR for 4 weeks	—

Countries

Japan

Contacts

Public Contactmanabu kubota

Asahi General Hospital Dept. of Gastroenterology

manabukuboa@hospital.asahi.chiba.jp0479-63-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026