Efficacy of cold snare polypectomy for the patients taking anticoagulants; Prospective, open label, randomized controlled trial.

Efficacy of cold snare polypectomy for the patients taking anticoagulants; Prospective, open label, randomized controlled trial. - Randomized controlled trial for cold snare polypectomy in patients taking anticoagulants.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022461

Enrollment

180

Registered

2016-06-01

Start date

2016-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-pedunculated subcentimetric colorectal polyp (adenoma or sessile serrated adenoma/polyp)

Interventions

Cold snare polypectomy for subcentimetric colorectal polyp taking anticoagulants Hot snare polypectomy for subcentimetric colorectal polyp with heparinization

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Patients who has subcentimetric colorectal polyp 2.Patients taking anticoagulant 3.Patients agreed to participate to the study after informed consent. 4.PS, 0,1 5.Plt, normal range. Cre, less than2.0mg/dl PT % more than 70% (In case of patients taking warfarin, the range of PT-INR should be within 1.5-3.0)

Exclusion criteria

Exclusion criteria: 1.Previous enrollment to this study. 2.Inflammatory bowel disease, polyposis patient. 3.Polyps larger than 10mm, lesions suspicious for cancer, pedunculate type polyp, or depressed type polyp. 4.Patients taking steroid, anti platelet, multiple anticoaglants. 5.Non-correctable coagulopathy 6.Pregnancy or lactating 7.Psychiatric disorder 8.Active infection 9.Non-correctable hypertention 10.Chronic respiratory failure 11.Undergo artificial dialysis 12.Inappropriate to participate to the study

Design outcomes

Primary

Measure	Time frame
Procedure related immediate and delayed bleeding rate.	—

Secondary

Measure	Time frame
Hematochezia rate (not requiring endoscopic hemostasis), Immediate bleeding rate, Mean procedure time, Mean hospitalization (for subcentimetric polyp, for all polyps), Number of total colonoscopy for clean colon, Adverse event.	—

Countries

Japan

Contacts

Public ContactYoji Takeuchi

Osaka International Cancer Institute Gastrointesitnal Oncology

takeuti-yo@mc.pref.osaka.jp06-6945-1181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026