Colorectal cancer
Conditions
Interventions
The dose of Seroshion is 1 capsule (10mg) after each meal,three times a day.We start the Seroshion administration at the first day of the chemotherapy,and also continue to intake it ,if you don'
t continue the chemotherapy. The end of chemotherapy is the end of Seroshion.
Sponsors
Osaka University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Patients diagnosed histologically colorectal cancer. 2)Curative resection,R0 was performed. 3)Patients are diagnosed pathological Stage3 at the postoperative time. 4)20 years older. 5)PS is 0 or 1. 6)Patients who don't receive the treatment except surgery. 7)Oral ingestion is possible. 8)Major organ function is checked by the clinical examination within 14 days. 9) Patients who can receive the treatment within postoperative 8 weeks. 10)The written consent is obtained.
Exclusion criteria
Exclusion criteria: 1) Patients who could not resect curatively. 2) Patients with active double cancer. 3) Patients with severe drug hypersensitivity, or with a history of drug allergy. 4) Patients with serious complications (heart failure, renal failure, liver failure, bleeding ulcer, watery diarrhea, intestinal paralysis, intestinal obstruction, severe diabetes). 5)Patients of cirrhosis with jaundice or of suspected cirrhosis of the liver. 6)Patients with the history of chronic hepatitis B and with the experience of Seroshion. 7)Patients with active infection. 8)Women with the possibility of pregnancy,during pregnancy,with the hope of pregnancy,or with breast-feeding. 9)Patients with mental severe disorder. 10)Other cases who doctor determines that patients are unsuitable for safely carrying out the present study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| safety | — |
Countries
Japan
Contacts
Public ContactMizushima Tsunekazu
Osaka University,Graduate School of Medicine Gastroenterological Surgery
Outcome results
None listed