Experiment for verification of the anti-fatigue effects of hydrogen-rich water in daily life: cross-over study.

Experiment for verification of the anti-fatigue effects of hydrogen-rich water in daily life: cross-over study. - The anti-fatigue effects of hydrogen-rich water.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022382

Enrollment

Registered

2016-05-20

Start date

2014-09-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Ingestion of test water for 4 weeks. / Wash out for 4 weeks. / Ingestion of placebo water for 4 weeks. Ingestion of placebo water for 4 weeks. / Wash out for 4 weeks. / Ingestion of test water for

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Healthy persons who are aged from 20 to 49 years. 2.Persons who are not shift worker.

Exclusion criteria

Exclusion criteria: 1.Pregnant women. 2.Persons who are in treatment. 3.Persons who have medical history of cardiovascular disease. 4.Persons who have medical history of nervous system disease such as unconsciousness, coma, and convulsion, etc. 5.Persons who have insomnia. 6.Persons who have food allergy. 7.Persons who are heavy user of alcohol. 8.Persons who are judged not suitable to participate in this trial by investigators.

Design outcomes

Primary

Measure	Time frame
Changes in subjective fatigue, autonomic nervous function, oxidation stress and antioxidant activity after 4 weeks.	—

Secondary

Measure	Time frame
Amount of activity Cognitive function	—

Countries

Japan

Contacts

Public ContactKei Mizuno

Osaka City University Center for Health Science Innovation

chsi-b@ado.osaka-cu.ac.jp06-6485-0288

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026