6% hydroxyethyl starch, tourniqutte application, total knee arthroplasty, ischemic-reperfusion syndrome
Conditions
Interventions
Before combined spinal anesthesia, the patients allocated in group HES, received intravenously 6% hydroxyethyl starch solution 10ml/kg(body weight).
Before combined spinal epidural anesthesia, the pat
Sponsors
National Health Insurance Corporation Ilsan Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: scheduled total knee arthroplaty unilateral under combined epidural-spinal anesthesia
Exclusion criteria
Exclusion criteria: emergency surgery uncontrolled hypertension, diabetes ASA class III, IV
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference of serum malondialdehide level before and after tourniqutte application in each group, 6% hydroxyethyl starch group and normal saline group. | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences of serum malondialdehide between the groups, 6%hydroxyethyl starch and normal saline group before and after tourniqutte application. Differences of serum total protein, albumin level between two groups before and after tourniqutte application. | — |
Countries
Asia(except Japan)
Contacts
Public ContactJAE HO LEE
National Health Institution Ilsan Hospital Department of Anesthesiology and Pain Medicine
Outcome results
None listed