gastric tumor
Conditions
Interventions
Vonoprazan Fumarate 20 mg once a day for 26days after ESD
Lansoprazole 30 mg once a day for 26days after ESD
Sponsors
Department of Gastroenterology and Hepatology Hokkaido University Graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: gastric tumor which meet indication of Gastric ESD
Exclusion criteria
Exclusion criteria: 1) Patient who cannot discontinue medicine such as PPI, H2blocker and gastroprotective for 1 week before ESD 2) Patients with history of surgery that affects gastric-acid secretion 3) Patients with Zollinger-Ellison syndrome 4) Patients cannot start oral administration 5) Patients with a history of allergy to the investigational product 6) Patients with a serious complication of liver failure 7) Patients with a serious complication of renal failure 8) Patients who cannot make their decision 9) Patients in pregnancy or may be pregnant 10) Patients during breastfeeding 11) Patients treated with atazanavir sulfate (Reyataz) or rilpivirine hydrochloride (Edurant) 12) Patient taking medicine such as theophylline, tacrolimus hydrate, digoxin, methyldigoxin, itraconazole, Gefitinib, methotrexate, phenytoin, Diazepam
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ratio of post-ESD scar after 4 weeks of gastric ESD | — |
Secondary
| Measure | Time frame |
|---|---|
| redaction ratio of post-ESD ulcer after 4 weeks of gastric ESD | — |
Countries
Japan
Contacts
Public ContactShuichi Miyamoto
Hokkaido University Graduate School of Medicine Department of Gastroenterology and Hepatology
Outcome results
None listed