Investigation of correlation between the findings of contrast-enhanced ultrasound and clinicopathological factors in breast cancer.

Investigation of correlation between the findings of contrast-enhanced ultrasound and clinicopathological factors in breast cancer. - Investigation of correlation between the findings of contrast-enhanced ultrasound and clinicopathological factors in breast cancer.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000022326

Enrollment

Registered

2016-05-17

Start date

2013-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with breast cancer who underwent CEUS in Ebetsu City Hospital. 2. Patients with histopathologically confirmed breast cancer who underwent mastectomy or breast-conserving surgery in Ebetsu City Hospital.

Exclusion criteria

Exclusion criteria: 1. Patients who underwent neoadjuvant chemotherapy. 2. Patients who did not undergo surgery. 3. Ineligible patients certified by principal investigator.

Design outcomes

Primary

Measure	Time frame
To investigate the correlation between CEUS characteristics, enhancement size compared with the original tumor size measured by plain B-mode imaging or enhancement intensity relative to surrounding normal breast tissue and grade of breast cancer indicating by nuclear grade and Ki67 index.	—

Secondary

Measure	Time frame
1. To analysis the correlation between CEUS characteristics, enhancement size compared with the original tumor size measured by plain B-mode imaging or enhancement intensity relative to surrounding normal breast tissue and age, tumor diameter, axillary lymph node metastasis, ER, PgR, HER2 expression, subtypes. 2. In surgical specimen, to investigate HE staining histopathological image in extended enhancement region and boundary region of equal or smaller enhancement.	—

Measure

Time frame

1. To analysis the correlation between CEUS characteristics, enhancement size compared with the original tumor size measured by plain B-mode imaging or enhancement intensity relative to surrounding normal breast tissue and age, tumor diameter, axillary lymph node metastasis, ER, PgR, HER2 expression, subtypes. 2. In surgical specimen, to investigate HE staining histopathological image in extended enhancement region and boundary region of equal or smaller enhancement.

—

Countries

Japan

Contacts

Public ContactMasatoshi Kadoya

Ebetsu City Hospital Surgery

mkado.6809@kib.biglobe.ne.jp011-382-5151

Outcome results