Healthy adults
Conditions
Interventions
The treatment group will receive oral administration of two jellies including 2 mg astaxanthin twice daily (8 mg astaxanthin/ 4 jellies /day) for 8 consecutive weeks.
The placebo group will receive o
Sponsors
JX Nippon Oil & energy Corporation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Age at the time of giving informed consent: 45 to 64 years
Exclusion criteria
Exclusion criteria: (1) Subjects who are difficult to discriminate color (2) Subjects with bad eyesight, or are diagnosed with amblyopia or blindness (3) Subjects with bad hearing, or are diagnosed with hearing loss or permanent hearing loss (4) Subjects who get a score of 20 or less on the Revised HDS-R (5) Subjects who smoke, or quit smoking within one year before pre-inspection (6) Subjects with history of cranial nerve disease (7) Subjects with depressive symptoms or history of them (8) Subjects who are under hormone treatment or are diagnosed with menopause (9) Subjects who have some irregular schedules during the study, due to night work or something (10) Subjects who drink much alcohol (11) Subjects who have done brain function test before (12) Subjects who are under treatment of brain function, sleep or stress, or are prescribed with medicine for them (13) Subjects who continuously take medicine, health foods, Food for Specified Health Uses or Foods with Function Claims including substance related to brain function, antioxidant, sleep or stress (14) Subjects who was given or donated 200 ml or 400 ml whole blood within three months before pre-inspection (15) Subjects who participated in other study within one month before pre-inspection, or are going to participate in other study during the study (16) Subjects who have a disease which needs regular medication, or have a history of the disease (17) Subjects who are judged as unsuitable for the study by investigator because of clinical test, anthropometric test and physical examination in pre-inspection (18) Subjects who are in danger of allergy to the ingredients of the test food (19) Subjects who are pregnant or lactating, or plan to become pregnant or lactate during the study (20) Subjects who are judged as unsuitable for the study because of lifestyle questionnaire (21) Subjects who are judged as unsuitable for the study by investigator for other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Memory test of words, Recall test of words and Stroop test | — |
Secondary
| Measure | Time frame |
|---|---|
| POMS VAS for fatigue Action of the bowels Serum concentration of astaxanthin | — |
Countries
Japan
Contacts
Public ContactMasahiro Hayashi
JX Nippon Oil & energy Corporation Biotechnology Business Group Biotechnology Business Unit Specialty Chemicals & Materials Company
Outcome results
None listed