N/A (healthy adults)
Conditions
Interventions
Sponsors
Anti-Aging Bank Co.,Ltd.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: [1]Japanese females after menopause aged 40-65 years [2]Individuals who are healthy and do not treat any disease(including a skin disease) [3]Individuals who are aware of skin elasticity or dullness [4]Individuals whose written informed consent has been obtained [5]Individuals who can have an examination on a designated check day [6]Individuals judged appropriate for the study by the principal
Exclusion criteria
Exclusion criteria: [1]Individuals using medical products [2]Individuals with absorption and an application custom of the medicine which had disease treatment for its object in the past 1 month (One-shot medicine of a headache, menstrual pain and a cold removes it.) [3]Individuals who have a history of serious hepatopathy, kidney damage, heart disease, lung disease,or blood disease [4]Individual who have digestive organ disease(disease of an appendix is removed) [5]Individuals whose systolic blood pressure is over 160mmHg or diastolic pressure is over 100mmHg [6]Individuals who donated blood over 200mL in the past 1 month or over 400mL in the past 3 months [7]Individuals with serious anemia [8]Individuals who are sensitive to test products or Individual with fear who causes severe allergy in a food and medical supplies [9]Individual who is pregnant or lactate [10]Individuals who are alcohol dependent or have other mental disabilities [11]Individuals with smoking habit [12]Individuals whose bowel habit is irregular [13]Individuals whose life style will change during the test period (ex. a night shift, travel for a long time) [14]Individuals of sensitive skin [15]Individuals with skin disease, such as atopic dermatitis [16]Individuals who have an inflammation or a scar on a measuring area [17]Individuals with probable seasonal allergy, such as pollinosis, during the test period and with a possibility that medical supplies are used (The eye drops and the nose drop are possible.) [18]Individuals who becomes negligent of skin care extremely (persons busy with work, domesticities and child care) [19]Individuals who will get sunburned during the test period etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin moisture content(4W,8W,12W) Transepidermal water loss(4W,8W,12W) Skin viscoelasticity(4W,8W,12W) Color-difference(4W,8W,12W) Image analysis by VISIA(12W) Skin AGE deposition(4W,8W,12W) d-ROMs Test(4W,8W,12W) BAP Test(4W,8W,12W) MDA-LDL(4W,8W,12W) 3-Deoxyglucosone(4W,8W,12W) CML(4W,8W,12W) Pentosidine in blood(4W,8W,12W) Insulin(4W,8W,12W) Pentosidine in urine(4W,8W,12W) Isoprostane(4W,8W,12W) 8-OHdG(4W,8W,12W) | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure, pulsation Weight, body fat percentage, BMI Hematological examination Blood biochemistry Urinalysis Doctor's questions Subject's diary Anti-Aging QOL Common Questionnaire | — |
Countries
Japan
Contacts
Public ContactToshiyasu Tamura
TES Holdings Co., Ltd. Department of Clinical Trial
Outcome results
None listed