Type 2 diabetes
Conditions
Interventions
After becoming stable on once-daily insulin degludec treatment, OD group was assigned to continue once-daily injection.
After becoming stable on once-daily insulin degludec treatment, TW group was swi
Sponsors
St. Marianna University School ofMedicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The inclusion criteria were the following relative indications for insulin treatment according to the Japan Diabetes Society: 1) detection of marked hyperglycemia (e.g., fasting plasma glucose > 250 mg/dL or casual plasma glucose > 350 mg/dL) in the non-insulin-dependent state, 2) failure to achieve good glycemic control with oral hypoglycemic agents, 3) deterioration of the nutritional status in a lean patient, or 4) to achieve active control of glucose toxicity when this is needed.
Exclusion criteria
Exclusion criteria: The exclusion criteria were the following absolute indications for insulin treatment: 1) an insulin-dependent state, 2) diabetic coma, 3) hyperglycemia complicated by severe liver or kidney disease, 4) serious infection, trauma, or major surgery, 5) intravenous alimentation. Patients who had no difficulty performing self-injection of insulin were also excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glycemic controlassessed by continuous glucose monitoring over 7 days | — |
Secondary
| Measure | Time frame |
|---|---|
| The percent duration of hypo- (<70 mg/dL and hyper- (>200 mg/dL) glycemia | — |
Countries
Japan
Contacts
Public ContactYoshio Nagai
St. Marianna University School of Medicine Division of Metabolism and Endocrinology, Department of Internal Medicine
Outcome results
None listed