The effect of sustained inflation in very low birth weight infants ventilated with high frequency oscillation: a randomized crossover trial.

The effect of sustained inflation in very low birth weight infants ventilated with high frequency oscillation: a randomized crossover trial. - The effect of sustained inflation in preterm infants with high frequency oscillation: a randomized crossover trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022158

Enrollment

Registered

2016-05-01

Start date

2016-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Very low birth weight infants

Interventions

With Sustained Inflation(SI)and without SI. 6 hours later,we change with SI(or without SI), 30minutes of wash out time, we observe 6 hours. With Sustained Inflation(SI)and without SI. 6 hours later,

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)Birth weight <1500g (2)ventilated with HFO(Babylog VN500) (3)age>1 week after birth (4)No change of ventilator settings (MAP,Amplitude,VT,frequency) (5)agreement of their parents to participate in this study

Exclusion criteria

Exclusion criteria: (1)unstable lung condition(i.e pneumonia, pneumothorax) (2)a case that attending physician consider inappropriate

Design outcomes

Primary

Measure	Time frame
The ratio of desaturation(SpO2<80%)	—

Secondary

Measure	Time frame
Heart rate Transcutaneous CO2 Cerebral and peripheral blood flow	—

Countries

Japan

Contacts

Public ContactMakoto Tamura

Takatsuki General Hospital Department of Pediatrics and Neonatology

mako0803qoo@gmail.com072-681-3801

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026