Two-dimension tailor-made eradication therapy as the third-line therapy for Helicobacter pylori infection.

Two-dimension tailor-made therapy (2dTMT): a new salvage therapy after multiple eradication failures for Helicobacter pylori infection. - Two-dimension tailor-made eradication therapy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022154

Enrollment

Registered

2016-05-01

Start date

2007-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infection

Interventions

A proton pump inhibitor and two antibiotics are prescribed.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are positive for H. pylori after twice or more eradication therapies.

Exclusion criteria

Exclusion criteria: Those who do not want to undergo eradication therapy anymore. Those who discontinued previous eradication therapies because of adverse events. Those who have severe liver or renal diseases or other conditions which are not adequate to enter the study.

Design outcomes

Primary

Measure	Time frame
Eradication success is evaluated 2 months or later after eradication therapy.	—

Secondary

Measure	Time frame
Safety is evaluated with adverse events during the therapy.	—

Countries

Japan

Contacts

Public ContactShigemi Nakajima

JCHO Shiga Hospital Department of General Medicine

shigemin@rainbow.plala.or.jp077-537-3101

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026