primary nephrotic syndrome
Conditions
Interventions
rituximab
Sponsors
Tokyo Metropolitan Geriatric Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patient whose age is more than 18 years old, and who is established the diagnosis of primary nephrotic syndrome.
Exclusion criteria
Exclusion criteria: Case that showed at least one of the following terms should be excluded. 1)Patient who have the severe allergy for rituximab. 2)Patient who has the severe disease, such as heart failure,liver diseases(hepatitis B positive)and end stage renal disease. 3)Patient who has the severe bacterial,fungal or viral infection. 4)Patient who could not experienced informd consent. 5)The doctor decides that the patient is inappropriate to enroll in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of remission from nephrotic syndrome | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Rate of continuity of the selected treatment. 2. The reduction of the degree of proteinuria. 3. Frequency of adverse complication derived from drug use. 4. Total dose of prednisolone and immunosuppressant agents for treatment of nephrotic syndrome. 5. Changes in the renal function | — |
Countries
Japan
Contacts
Public ContactTakashi Takei
Tokyo Metropolitan Geriatric Hospital Nephrology
Outcome results
None listed