Healthy adult
Conditions
Interventions
Amino acid mixture, single ingestion - Wash out 1 week - Placebo, single ingestion
Placebo, single ingestion - Wash out 1 week - Amino acid mixture, single ingestion
Sponsors
CPCC Company Limited
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) Subjects who can make self-judgment and are voluntarily giving written informed consent. 2) Subject who can use personal sauna bath without unreasonable. 3) Healthy males aged 20 to 49 years old, who meet the followings at the day of screening test. (1) Subjects who regarded as appropriate by the doctor from the results of screening test. (2) Healthy males who have BMI value between 18.5 and 25.0. (3) Health males who can conduct the cognitive function test.
Exclusion criteria
Exclusion criteria: 1) Subjects who have previous and/or current medical history of malignant tumor, heart failure, myocardial infarction. 2) Subjects who have chronic disease and who are given continuous treatment by taking medicines. 3) Subjects who took drugs, quasi drugs, or supplements those concern about influence to the test results on daily basis within 3 month before screening test. Or, subjects who plan to take those drugs, quasi drugs, or supplements during test period. 4) Subjects who have previous medical history of drug and/or food allergy. 5) Subjects who difficult to sweat in sauna bath. 6) Subjects who excessive alcohol intake. (intake over 60g alcohol per day) 7) Subjects who have tattoo. 8) Subjects who have wide barns scar. 9) Subjects who removing hair. 10) Subjects who participated within 3-month prior to the current study and/or who plan to participate the other clinical tests. 11) Others who have been determined ineligible by principal investigator or sub-investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Physiological index and refreshing feeling,on the day of the single ingestion. *Blood flow of skin surface *Amount of sweat *Body surface temperature *Visual analog scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Physiological index,on the day of the single ingestion. *Tympanic temperature *Acceleration pulse wave Blood test,on the day of the single ingestion. *Metabolite of nitric oxide *Cortisol *Free fatty acid Cognitive function test, on the day of the single ingestion. | — |
Countries
Japan
Contacts
Public ContactMakoto Ichinohe
CPCC Company Limited Plan Sales Department
Outcome results
None listed