Quality of life improvement of mild knee pain effect verification study in healthy Japanese adults: a double-blind randomized controlled trial

Quality of life improvement of mild knee pain effect verification study in healthy Japanese adults: a double-blind randomized controlled trial - Quality of life improvement of mild knee pain effect verification study in healthy Japanese adults

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022084

Enrollment

Registered

2016-04-26

Start date

2016-04-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Duration: 4 weeks Test material: Krill oil capsule Dose: 4 capsules, once a day Administration: Take 4 capsules after breakfast Duration: 4 weeks Test material: Krill oil and safflower oil capsu

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Healthy Japanese adults 2. Persons have mild knee pain

Exclusion criteria

Exclusion criteria: 1. At least one previous medical history of malignant tumor, heart failure or myocardial infarction 2. Currently under the treatment for either atrial fibrillation, cardiac arrhythmia, hepatic disorder, renal disorder, cerebrovascular disorder, knee osteoarthritis, rheumatism, diabetes mellitus, dyslipidemia, hypertension or other chronic diseases. 3. Currently taking medicines (include herbal medicines), and/or supplements, particularly taking acetylsalicylic acid or warfarin medicines 4. Allergic to medicines or foods related to the test food of this trial (shellfish and gelatin allergic for the test food contains crustacean-originating ingredient and is coated with gelatin-containing capsule film.) 5. Pregnant, lactating, or planning to get pregnant during the trial period 6. Enrolled into other clinical trials within the last 3 months before agreeing to participate in this trial 7. Judged unsuitable for participating in this trial by physician

Design outcomes

Primary

Measure	Time frame
Japanese Knee Osteoarthritis Measure (JKOM) *Measuring point: at 0 week and 4 weeks after ingestion	—

Secondary

Measure	Time frame
The scoring system of the Japanese Orthopaedic Association (JOA) High sensitivity C-reactive protein (hs-CRP) *Measuring point: at 0 week and 4 weeks after ingestion	—

Countries

Japan

Contacts

Public ContactNaoko SUZUKI

ORTHOMEDICO, Inc. R&D Department

nao@orthomedico.jp03-3818-0610

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026