Normal volunteers
Conditions
Interventions
Dose:105-740MBq
Sponsors
Hokkaido University Hospital
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Normal volunteers (1)aged 20-60 years old at agreement acquisition. (2)gave a written informed consent. (3)are nonsmokers or the persons who are available for smoking cessation during this study (4)are nondrinkers or the persons who are available for temperance during this study
Exclusion criteria
Exclusion criteria: (1) The person who is abnormal in laboratory study at screening. White blood cell differentiation is excluded) (2)a history of blood, heart, hepatic or renal disease. (3)The person who had an acute disease symptom (nausea, vomiting, fever, diarrhea) within 3 days before screening test (4)any medical treatment including vitamin drug and Kanpo-drug within 7 days before enrollment. (5)a donation of plasma to a blood bank or clinical study within 7 days before enrollment. a donation of over 200 ml whole blood to a blood bank or clinical studywithin 28 days before enrollment. a donation of over 400 ml whole blood to a blood bank or clinical study within 84 days before enrollment. a donation of over 800 ml whole blood to a blood bank or clinical study within 365 days before enrollment. (6) a history of hypersensitivity for medical drugs. (7)a participation in other clinical trials at present or other clinical trial within 6 months before enrollment. (8) a history of drug abuse or alcoholism. (9)The person of the severe claustrophobia. (10) The person who has a history of the poor physical condition by the medical act including drawing blood, the injection (11)and subjects were excluded if the investigators judged as misfit for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To clarify the presence or the absence, the type, the severity, and frequency of adverse effects and to assess the causal relationship. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pharmacokinetics Exposure dose | — |
Countries
Japan
Contacts
Public ContactTohru Shiga
Hokkaido University, Graduate School of Medicine Department of Nuclear Medicine
Outcome results
None listed