The effect of High Flow Nasal Cannula (HFNC) on end-expiratory lung volume in acute lung injury patients

The effect of High Flow Nasal Cannula (HFNC) on end-expiratory lung volume in acute lung injury patients - Lung volume during HFNC

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022020

Enrollment

Registered

2016-06-01

Start date

2016-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients with acute lung injury

Interventions

Aplly HFNC to the patients with ALI and monitor lung volume by EIT (Electrical impedance tomograpy)for 24 hours during HFNC Evaluate the changes in lung volume with different flow rates of HFNC (10,2

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)ALI (Respiratory rate >25/min, SpO2 <96%) 2)Impaired oxygenation with P/F ratio <300mmHg 3)Within 48 hours since diagnose of ALI 4)Written informed consent

Exclusion criteria

Exclusion criteria: 1)Impaired lung function (COPD grade > 3, or FEV1s < 1000ml) 2)Severly impaired oxgenation with P/F ratio <150mmHg 3)Chronic heart failure (Cardiac index < 1.8L/m2, NYHA > or = 3 ) 4)Unstable hemodynamics (mean arterial pressure < 50mmHg) 5)Glasgow Coma Scale <8

Design outcomes

Primary

Measure	Time frame
increase in end-expiratory lung volume during HFNC (high flow nasal canula)	—

Countries

Japan

Contacts

Public Contactatsuko shono

Shimane University Department of Anesthesiology, Faculty of medicine

atsuko929shono@yahoo.co.jp09094622098

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026