Clinical investigation of the effect of refined deepsea water on the human gut immunity.

Clinical investigation of the effect of refined deepsea water on the human gut immunity. - Clinical investigation of the effect of refined deepsea water on the human gut immunity.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000022002

Enrollment

100

Registered

2016-04-21

Start date

2015-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adults

Interventions

Ingestion of refined deepsea water (Hardness 1000) for 12 weeks (1L/1Day) Ingestion of mineral water for 12 weeks (1L/1Day)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy adults (20 years-old <=)

Exclusion criteria

Exclusion criteria: (1) Subject who are under treatment or have a history of needing medical treatment. (2) Subjects who plan to go overseas more than one week during study period. (3) Subjects who routinely drink refined deepsea water. (4) Subjects who are judged as unsuitable for the study based on the results of lifestyle questionnaire. (5) Subjects who are judged as unsuitable for the study by physician for any other reasons.

Design outcomes

Primary

Measure	Time frame
Comparative analyses between two groups (refined deepsea water vs. control water): Endpoints; changes of intestinal microbiota, decomposed matters and secretary IgA in feces, and equol in urine.	—

Secondary

Measure	Time frame
Improvement effect of symptoms including intestinal function.	—

Countries

Japan

Contacts

Public ContactSatoshi Ishizuka

Kochi University Center for Regional Collaboration (CRC)

zuka@kochi-u.ac.jp088-844-8555

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026