Multicenter prospective study on the usefulness and safety of edoxaban replacement before the endoscopic therapy with high-risk bleeding group during anticoagulant therapy with warfarin

Multicenter prospective study on the usefulness and safety of edoxaban replacement before the endoscopic therapy with high-risk bleeding group during anticoagulant therapy with warfarin - Disestive disorders requiring the endoscopic therapy in high-risk bleeding group

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021973

Enrollment

180

Registered

2016-04-18

Start date

2016-04-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Disestive disorders requiring the endoscopic therapy in high-risk bleeding group

Interventions

edoxaban replacement in high-risk bleeding group from anticoagulant therapy with warfarin. heparin replacement in high-risk bleeding group from anticoagulant therapy with warfarin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients in the anticoagulation therapy with warfarin is needed the endoscopic therapy in high-risk bleeding group, and meet following criteria: 1)The patient written consent has been obtained 2)The patient over the age of 20 3) The patient&#39;s platelet 50000 / mm3 or more

Exclusion criteria

Exclusion criteria: 1) The patient who has taken warfarin after heart valve replacement 2) The patient with severe comorbidity 3) The patient cannot be obtained with informed consent 4) The patient prohibited the participant of this study by their research investigator

Design outcomes

Primary

Measure	Time frame
The frequency of bleeding for 2 weeks after the endoscopic therapy	—

Secondary

Measure	Time frame
The frequency of thrombotic events	—

Countries

Japan

Contacts

Public ContactShinichi Hashimoto

Kagoshima University Digestive and Lifestyle Diseases

kumdsh@m.kufm.kagoshima-u.ac.jp0992755326

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026