The evaluation of activity, inflammation, and oxidative stress in patients with nontuberculous mycobacteriosis

The evaluation of activity, inflammation, and oxidative stress in patients with nontuberculous mycobacteriosis - Activity and oxidative stress of nontuberculous mycobacteriosis

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021956

Enrollment

200

Registered

2016-04-20

Start date

2016-04-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nontuberculous mycobacteriosis(NTM)

Interventions

Standard therapy by antibiotics(clarithromycin, rifampicin, ethambutol)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are diagnosed as NTM, as defined by the 2008 JST and JRS NTM criteria, and NTM-suspected cases due to their imaging analysis.

Exclusion criteria

Exclusion criteria: 1. Patients who disagree with involving in this study 2. Patients who diagnosed as malignancy, overt cardiac failure, and hepatic and renal disease 3. Patients who are judged to be unfit to the study

Design outcomes

Primary

Measure	Time frame
Oxidative stress markers (oxidants & antioxidants)	—

Secondary

Measure	Time frame
Disease activity, Inflammatory markers (cytokines, growth factors, proteases), Circadian rhythm (molecularclock) markers, Nutrition, Pulmonary function, Exercise capacity	—

Countries

Japan

Contacts

Public ContactSHUJI OH-ISHI

National Hospital Organization Ibarakihigashi National Hospital Department of Respiratory Medicine

ooishi.shuji.dg@mail.hosp.go.jp+81-29-282-1151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026