A randomized control trial of heparin bridging versus direct oral anticoagulant (DOAC) replacement in patients who undergo endoscopic resection for colon polyps. (NHOG-DOAC-EMR)

A randomized control trial of heparin bridging versus direct oral anticoagulant (DOAC) replacement in patients who undergo endoscopic resection for colon polyps. (NHOG-DOAC-EMR) - A randomized control trial of heparin bridging versus direct oral anticoagulant (DOAC) replacement in patients who undergo endoscopic resection for colon polyps. (NHOG-DOAC-EMR)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021947

Enrollment

160

Registered

2016-04-18

Start date

2016-05-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon polyp

Interventions

Heparin bridging before endoscopic mucosal resection direct oral anticoagulant replacement before endoscopic mucosal resection

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Patients who undergo endoscopic mucosal resection for colon polyps 2)Patients with non valvular atrial fibrillation, and use warfarin for prevention of thrombosis 3)PT-INR is less than 3.0 4)ages over 20 years 5)written informed consent

Exclusion criteria

Exclusion criteria: 1)Plt is less than 50000/mm3 2)Patients who undergo hemodialysis 3)Woman who has a possibility of pregnancy or is during pregnancy 4)Impossible to suspend to one-antiplatelet medication. 5)The attending physician has determined that it is difficult to entry

Design outcomes

Primary

Measure	Time frame
Post polypectomy bleeding rate	—

Secondary

Measure	Time frame
Hospitalization, endoscopic treatment results, the rate of arterial thromboembolism, severe adverse events, endoscopic execution rate	—

Countries

Japan

Contacts

Public ContactTakuya Yamada

National Hospital Organization Osaka National Hospital Gastroenterology and Hepatology

yamada@onh.go.jp06-6942-1331

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026