Patients who were scheduled to undergo elective unilateral pulmonary lobectomy or segmentectomy under general anesthesia combined with thoracic paravertebral block for a lung cancer.
Conditions
Interventions
Patinets will receive ultrasound-guided thoracic paravertebral block using 0.25%, 1 mg/kg of levobupivacaine.
Patinets will receive ultrasound-guided thoracic paravertebral block using 0.25%, 1 mg/kg
Sponsors
Wakayama Medical University
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1)Patients who are scheduled for unilateral pulmonary lobectomy or segmentectomy under general anesthesia combined with thoracic paravertebral block in Wakayama medical university hospital. 2)American Society of Anethesiologists physical status in 1, 2 or 3. 3)Patients who can give written informed consent.
Exclusion criteria
Exclusion criteria: 1)Patients who have contraindication of thoracic paravertebral block. 2)Patients who have allergy to the drugs which will going to use in this trial. 3)Patients who are regarded ineligible by doctors with ather reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The plasma concentration of levobupivacaine was measured at 1, 2.5, 5, 7.5, 10, 12.5, 15, 20, 30, 45, 60, 90, 120 and 150 minutes after paravertebral block. The peak plasma concentration and the time to peak plasma concentration for levobupivacaine were recorded directly from the measured values. The area under the plasma concentration time curve was calculated using the trapezoidal rule. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain:Numerical Rating Scale at rest and at cough after 6,12, 24, 48, and 72 hours postoperation. | — |
Countries
Japan
Contacts
Public ContactAkinori Yamazaki
Wakayama Medical University Hospital Department of Anesthesiology
Outcome results
None listed