The study to investigate quantitative neurological examinations for diagnosis and staging of diabetic polyneuropathy

The study to investigate quantitative neurological examinations for diagnosis and staging of diabetic polyneuropathy - The quantitative assessments of diabetic polyneuropathy

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000021916

Enrollment

Registered

2016-04-16

Start date

2016-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic polyneuropathy

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Group 1: non-diabetic patients Group 2: type 2 diabetic patients with HbA1c<13.0%

Exclusion criteria

Exclusion criteria: 1. Pregnancy, lactation 2. Severe infection, Severe injuries 3. Treatment with steroids 4. Current/Past malignancy 5. Allergic to anesthetic drugs 6. Inappropriate patients for entry on this study in the judgement of the investigator

Design outcomes

Primary

Measure	Time frame
1. Corneal confocal microscopic findings 2. Nerve conduction studies	—

Secondary

Measure	Time frame
1. Score of Michigan Neuropathy Screening Instrument(MNSI) 2. Clinical findings: i) Absent or hypoactive Achilles tendon reflexes, ii) Impaired vibration sensation 3. HbA1c, blood glucose 4. Coefficients of variance of RR intervals 5. Diabetic nephropathy, Diabetic retinopathy 6. Laboratory data, blood pressure 7. Safety 8. Current potential threshold 9. Iriscorder 10. Elctroretinography	—

Countries

Japan

Contacts

Public ContactHideki Kamiya

Aichi Medical University Diabetes

hkamiya@aichi-med-u.ac.jp0561-63-1683

Outcome results