The opportune time for periarticular injection during total knee arthroplasty under general anesthesia: a randomized controlled trial

The opportune time for periarticular injection during total knee arthroplasty under general anesthesia: a randomized controlled trial - The opportune time for periarticular injection during total knee arthroplasty under general anesthesia: a randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021910

Enrollment

Registered

2016-04-14

Start date

2016-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of the knee, rheumatoid arthritis, avascular necrosis

Interventions

Superficial injection after the implantation of prosthesis Superficial injection just prior to the arthrotomy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients scheduled for unilateral total knee arthroplasty

Exclusion criteria

Exclusion criteria: Patients scheduled for simultaneous bilateral total knee arthroplasty. Patients who had allergy or intolerance to one of the study drugs, regular narcotic use, renal insufficiency and prolonged QT interval on ECG.

Design outcomes

Primary

Measure	Time frame
Pain score (Visual analogue scale) at recovery room	—

Secondary

Measure	Time frame
Pain score (Visual analogue scale) 3 and 6 hours after surgery and 1 day after surgery Blood loss Complications The consumption of remifentanil The use of naloxone	—

Countries

Japan

Contacts

Public ContactSachiyuki Tsukada

Hokusuikai kinen hospital Orthopaedic surgery

s8058@nms.ac.jp029-303-3003

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026