Identifying of index cancer among multiple cancer foci by methylation analysis using the ex vivo prostate needle biopsy from prostatectomy specimen

Identifying of index cancer among multiple cancer foci by methylation analysis using the ex vivo prostate needle biopsy from prostatectomy specimen - Identifying of index cancer by the prostate needle biopsy

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021903

Enrollment

Registered

2016-06-01

Start date

2016-12-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

prostate cancer

Interventions

Methylation analysis of prostate normal tissue and cancer tissue from multiple cancer foci, which are taken from ex vivo prostatectomy specimens by needle biopsy technique

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1) The patients who had histologically-confirmed prostate adenocarcinoma, agreed to undergo radical prostatectomy. 2) The patients had MR-visible prostate cancer lesion, confirmed by MRUS fusion biopsy. 3) The patients signed by themselves the informed consent document after understanding this study.

Exclusion criteria

Exclusion criteria: Exclusion criteria:. 1) Prior or concurrent chemotherapy or androgen deprivation therapy for the prostate cancer. 2) Prior radiotherapy to the prostate or lower pelvis 3) Concurrent systemic steroids therapy for different disease 4) Unsuitable for participant due to mental disorder 5) The attending physician has determined inappropriate

Design outcomes

Primary

Measure	Time frame
To identify the index cancer which determine the patient prognosis among the multiple prostate cancer foci with methylation analysis using ex vivo needle biopsy specimens to compare between prostate normal tissue and prostate cancer tissue	—

Countries

Japan

Contacts

Public ContactMasakatsu Oishi

Kyoto Prefectural University of Medicine Urology

uro@koto.kpu-m.ac.jp075-251-5595

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026