Skip to content

Effect of high-flow nasal cannula therapy on exercise tolerance in patients with stable interstitial lung disease

Effect of high-flow nasal cannula therapy on exercise tolerance in patients with stable interstitial lung disease - High-flow nasal cannula therapy for stable interstitial lung disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000021901
Enrollment
20
Registered
2016-04-13
Start date
2016-04-14
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Interstitial lung disease

Interventions

Arm A Symptom limited incremental exercise tests were performed on electrically braked cycloergometer with room air or each oxygen flow at rest. On the following day, using a randomized, crossover pr

Sponsors

Department of Respiratory Medicine and Allergy, Tosei General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with stable interstitial lung disease who have oxygen desaturation (SpO2 lower than 88%) during treadmill exercise tolerance test on room air or each oxygen flow at rest. 2. Patients who agree to participate in the study with the written informed consent.

Exclusion criteria

Exclusion criteria: 1.Patients with obstructive pulmonary disease (FEV1/FVC lower than 0.7) 2.Patients with pneumothorax and/or pneumomediastinum 3.Patients with unstable diseases or the history of acute exacerbation within the last 1 month. 4.Patients with diseases affecting the outcome who regarded as inadequate for the study by the investigators. 5.Patients who have participated in the other study at the time of the informed consent, or will participate in the other study. 6.Any other patients who are regarded as inadequate for the study enrollment by the investigators.

Design outcomes

Primary

MeasureTime frame
Endurance exercise time

Secondary

MeasureTime frame
1. Dyspnea intensity on exertion (modified Borg scale) 2. Desaturation during exertion(SpO2) 3. Maximum heart rate during exertion 4. Patient comfort during exertion (NRS scale) 5. Adverse events

Countries

Japan

Contacts

Public ContactAtsushi Suzuki

Tosei General Hospital Department of Respiratory Medicine and Allergy

atsushi-salyu@hotmail.co.jp0561-82-5101

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026