Interstitial lung disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with stable interstitial lung disease who have oxygen desaturation (SpO2 lower than 88%) during treadmill exercise tolerance test on room air or each oxygen flow at rest. 2. Patients who agree to participate in the study with the written informed consent.
Exclusion criteria
Exclusion criteria: 1.Patients with obstructive pulmonary disease (FEV1/FVC lower than 0.7) 2.Patients with pneumothorax and/or pneumomediastinum 3.Patients with unstable diseases or the history of acute exacerbation within the last 1 month. 4.Patients with diseases affecting the outcome who regarded as inadequate for the study by the investigators. 5.Patients who have participated in the other study at the time of the informed consent, or will participate in the other study. 6.Any other patients who are regarded as inadequate for the study enrollment by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Endurance exercise time | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Dyspnea intensity on exertion (modified Borg scale) 2. Desaturation during exertion(SpO2) 3. Maximum heart rate during exertion 4. Patient comfort during exertion (NRS scale) 5. Adverse events | — |
Countries
Japan
Contacts
Tosei General Hospital Department of Respiratory Medicine and Allergy