The study on the safety of perchlorate discharge test for Pendred syndrome patients

The study on the safety of perchlorate discharge test for Pendred syndrome patients - The study on the safety of perchlorate test

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021900

Enrollment

Registered

2016-04-19

Start date

2016-02-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pendred syndrome

Interventions

Intake rate test by schincigraphy is performed 3 hrs after induction of 123I intake. Perchlorate (20 mg/kg for over 3 years old (e.g.0.6 g for 6 years old) and 1.0 g for over 50 kg body weight or adul

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients who are eligible to the follosing criteria. 1) Pendred syndrome suspected patients with sensorineural hearing loss and thyroid goiter. 2) Patients or their guardians if the patients are children who understand our explanation completely with written informed consent signed and dated.

Exclusion criteria

Exclusion criteria: 1) Patients who do not consent to our study. 2) Patients judged by investigators ineligible due to seriousness of patients condition.

Design outcomes

Primary

Measure	Time frame
To assess the safety. Intake rate test by scintigraphy is performed 3 hrs after 123I intake.	—

Secondary

Measure	Time frame
To assess the efficacy. Intake rate and thyroid function tests are performed after perchlorate administration.	—

Countries

Japan

Contacts

Public ContactHisashi Koide

Chiba University Graduate School of Medicine Clinical Cell Biology and Medicine

koideh@chiba-u.jp043-222-7171

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026