Effects of flurbiprofen on the hypotension following to thoracotomy.

Effects of flurbiprofen on the hypotension following to thoracotomy. - Effects of flurbiprofen on the hypotension following to thoracotomy.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021872

Enrollment

Registered

2016-04-11

Start date

2016-04-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elective lung resection cases

Interventions

Flurubiprofen administration on anesthesia induction Flurbiprofen administration on wound closure

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Elective lung resection cases scheduled for left thoracotomy

Exclusion criteria

Exclusion criteria: History of flurbiprofen allergy Active asthma Chronic kidney disease

Design outcomes

Primary

Measure	Time frame
Intraoperative blood pressure	—

Secondary

Measure	Time frame
Intraoperative heart rate Intraoperative dose of phenylephrine and ephedrine Intraoperative infusion, transufusion, urine output, blood loss and fluid balance (ml/kg/h) Postoperative dose of flurbiprofen. Postoperative dose of phenylephrine. Postoperative infusion, transufusion, urine output, blood loss and fluid balance (ml/kg/h). Count of blood cells(WBC, RBC, hemoglobin, platelets) and biochemical tests (Alb, AST, ALP, LDH, BUN, Cr, CRP) on 1 and 7 postoperative day. ICU stay days. Hospital stay days.	—

Measure

Time frame

Intraoperative heart rate Intraoperative dose of phenylephrine and ephedrine Intraoperative infusion, transufusion, urine output, blood loss and fluid balance (ml/kg/h) Postoperative dose of flurbiprofen. Postoperative dose of phenylephrine. Postoperative infusion, transufusion, urine output, blood loss and fluid balance (ml/kg/h). Count of blood cells(WBC, RBC, hemoglobin, platelets) and biochemical tests (Alb, AST, ALP, LDH, BUN, Cr, CRP) on 1 and 7 postoperative day. ICU stay days. Hospital stay days.

—

Countries

Japan

Contacts

Public ContactHiromi Katoh

Hyogo Cancer Center Department of Anesthesia

whoami@hp.pref.hyogo.jp0789291151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026