Exploratory study on detecting EGFR mutation including T790M with blood samples from patients with advanced non-small cell lung cancer after EGFR-TKI failure

Exploratory study on detecting EGFR mutation including T790M with blood samples from patients with advanced non-small cell lung cancer after EGFR-TKI failure - EGFR mutation analysis including T790M for blood samples

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000021860

Enrollment

120

Registered

2016-04-11

Start date

2016-04-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Advanced non-small cell lung cancer with EGFR mutation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Pathologically confirmation of non-small cell lung cancer 2) EGFR gene mutations are identified 3) Refractory to EGFR-TKI monotherapy or combination therapy 4) Written informed consent

Exclusion criteria

Exclusion criteria: Not applicable

Design outcomes

Primary

Measure	Time frame
Detection rate of EGFR mutations including T790M in plasma	—

Secondary

Measure	Time frame
1) Concordance of EGFR mutation status between tissue samples and plasma 2) Correlation between EGFR mutation status and clinical background	—

Countries

Japan

Contacts

Public ContactTakahisa Kawamura/ Murakami Haruyasu

Shizuoka cancer center Devision of Thoracic Oncology

ta.kawamura@scchr.jp(+81)055-989-5222

Outcome results