The relationship between end-tidal desflurane concentration and threshold current of motor-evoked potential(MEP) under general anesthesia with propofol and remifentanil

The relationship between end-tidal desflurane concentration and threshold current of motor-evoked potential(MEP) under general anesthesia with propofol and remifentanil - The relationship between end-tidal desflurane concentration and threshold current of motor-evoked potential(MEP)

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021851

Enrollment

100

Registered

2016-05-10

Start date

2014-11-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients undergoing spine surgery

Interventions

Desflurane is combined at end-tidal concentration of 1, 2, 3 and 4% with propofol and remifentanil for general anesthesia and MEP threshold current is measured respectively.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing spine surgery

Exclusion criteria

Exclusion criteria: Patients with motor palarysis Patients with comorbidity American Society of Anesthesiologists physical status(ASA-PS)3 or more Patients whom investigators consider to be ineligible

Design outcomes

Primary

Measure	Time frame
Desflurane is combined at end-tidal concentration of 1, 2, 3 and 4% with propofol and remifentanil for general anesthesia and MEP threshold current is measured respectively after five minutes steady state.	—

Countries

Japan

Contacts

Public ContactTAKEHIKO NAGAOKA

Shin-yurigaoka General Hospital Anesthesia

takeitezzz@gmail.com0443229991

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026