Borderline of Fatty liver
Conditions
Interventions
One Capsule a day which contain 2mg of polymethoxy flavonoid
One Capsule a day which contain no polymethoxy flavonoid
Sponsors
ARKRAY, Inc.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Japanese healthy volunteer (20<=age<75, male and female) 2)borderline of fatty liver 3)Those who are suitable for this trial by doctor decision. 4)Those Who can ingest the test food during the trial 5) Those who continue one&#39;s excise and/or diet therapy if needed. 6) Those who can give informed consent by the document.
Exclusion criteria
Exclusion criteria: 1)Viral hepatitis patient, alcoholic hepatitis patient, autoimmune liver damage patient 2)BMI>=30 3)Heart failure, myocardial infarction with a history of the past of the treatment 4)Those who takes medicine for antihypertensive drug, lipidosis symptom therapeutic drug, diabetes therapeutic drug, livers 5)Those who are under treatment for atrial fibrillation, arrhythmia, a liver damage, a renal damage, cerebrovascular disorder, rheumatism, diabetes, dyslipidemia, high blood pressure 5)Those who suffer any severe disease diagnosised by the responsible doctor. 6) Those who drink more than 20 grams alcohol a day everyday (beer 500 ml or sake around 1 go) 7) Those who takes a supplement regularly. 8) Those who have food allergy. 9) Those who is in breast-feeding or pregnancy, or wishes to become pregnant during the study period. 10) Those who had participated in a clinical trial within 30 days before a screening test. 11) Those who is judged as ineligible by principal investigators or researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AST, ALT,gammaGTP,QOL | — |
Secondary
| Measure | Time frame |
|---|---|
| BMI, percent of body fat, girth of the abdomen, quantity of muscle, HOMA-IR, acylglycerol, total cholesterol HDL cholesterol, LDL cholesterol, blood sugar level, HbA1c, insulin, sLOX-1, cys-TTR, arteriosclerosis index, nonHDL cholesterol, genetic test,ferritin,type4-collagen7S | — |
Countries
Japan
Contacts
Public ContactHirosato Kawakami
Karada Lab, Inc. The Director of the Laboratory
Outcome results
None listed