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Examination of the relationship between Alzheimer's disease and arteriosclerosis

Examination of the relationship between Alzheimer's disease and arteriosclerosis - Examination of the relationship between Alzheimer's disease and arteriosclerosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000021792
Enrollment
90
Registered
2016-04-07
Start date
2016-04-11
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer&amp

Interventions

Arteriosclerosis-related tests, cerebrospinal fluid tests, examination of cognitive function, blood tests

Sponsors

Department of Biological Regulation, School of Health Science, Faculty of Medicine, Tottori University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Subjects who are 20-89 years old at the time of registration 2) Alzheimer's disease patients who fulfill of the DSM-5 and NINCDS-ADRDA criteria, or mild cognitive impairment patients who fulfill of the Petersen criteria, or subjects who don't have cognitive impairment. 3) In the Alzheimer's disease and mild cognitive impairment patients, the consent from proxies is necessary. 4) Patients who performed the cerebrospinal fluid and blood tests (total cholesterol, LDL cholesterol, HDL cholesterol, triglyceride, glucose) within three months.

Exclusion criteria

Exclusion criteria: 1) Patients who are judged difficulty depiction of brachial artery or pressure of forearm. 2) Patients who have more than 200 mmHg in resting systolic pressure. 3) Patients who are assessed by the principal investigator due to other reasons.

Design outcomes

Primary

MeasureTime frame
Arteriosclerosis-related tests (Flow Mediated Dilation:FMD, Arterial Pressure volume Index:API, Arterial Velocity pulse Index:AVI), cerebrospinal fluid tests, Touch Panel-type Dementia Assessment Scale(TDAS)—

Secondary

MeasureTime frame
Blood tests (total cholesterol, LDL cholesterol, HDL cholesterol, triglyceride, glucose)—

Countries

Japan

Contacts

Public ContactMinoru Kouzuki

School of Health Science, Faculty of Medicine, Tottori University Department of Biological Regulation

kouzuki@med.tottori-u.ac.jp0859-38-6358

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026