Neonatal respiratory distress syndrome
Conditions
Interventions
Place the infant inside the incubator and start nasal continuous positive airway pressure. Displace one of the prongs, and insert the bronchoscope from the open nostril. Place the tip of the bronchosc
Sponsors
Tokyo Women's Medical University Adachi Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients fulfilling all of the following criteria will be included 1. Patients born at Tokyo Women's Medical University Medical Center East, and admitted to the NICU 2. Patients diagnosed with respiratory distress syndrome 3. Informed consent obtained from parents 4. Patients thought to be appropriate for the study by the attending physician
Exclusion criteria
Exclusion criteria: Patients fulfilling any of the following criteria will be excluded 1. Patients with severe birth asphyxia 2. Patients with multiple malformation syndrome, or other suspected underlying diseases 3. Patients needing vasoactive drugs 4. Patients with tendency to bleed 5. Patients with congenital infections 6. Patients thought to be inappropriate for the study by the supervising physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Short term prognosis of respiration in patients treated with bronchoscopic MIST. Short term prognosis of respiration includes the following 1. Days under mechanical ventilation 2. Days under supplemental oxygen 3. Incidence of airway diseases 4. Need for endotracheal intubation or additional surfactant | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Morbidity of diseases often seen in premature infants(intraventricular hemorrhage, pneumothorax, patent ductus arteriosus, bronchopulmonary dysplasia, sepsis, necrotizing enterocolitis) 2. Length of hospitalization, mortality rate | — |
Countries
Japan
Contacts
Public ContactMasanori Wasa
Tokyo Women's Medical University Adachi Medical Center Neonatology
Outcome results
None listed