Kidney disease, hypertension, cardiovascular disease
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who are going to undergo renal biopsy for the scrutiny of kidney disease, and those who already underwent renal biopsy for the same purpose. 2. Patients who already underwent nephrectomy and whose resected renal tissues are preserved in the tissue repository.
Exclusion criteria
Exclusion criteria: Patients who are considered inappropriate for inclusion in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The distribution of LRG1 in the normal kidney tissues of dissected kidney by nephrectomy and in the renal biopsy specimens derived from diseased kidney, and its relationship with parameters of renal function, CKD CGA classification, diabetic nephropathy classification, and renal events (serum creatinine doubling, dialysis induction and total mortality. | — |
Secondary
| Measure | Time frame |
|---|---|
| Parameters of renal and cardiovascular function, glucose, lipid and electrolyte metabolism, renin-angiotensin system, urinary fibrotic and inflammatory factors, and ambulatory blood pressure monitoring. | — |
Countries
Japan
Contacts
Yokohama City University Graduate School of Medicine Department of Medical Science and Cardiorenal Medicine