Efficacy of multidrug-resistant Lactobacillus preparation on variation of intestinal bacterial flora caused by antibiotic therapy

Efficacy of multidrug-resistant Lactobacillus preparation on variation of intestinal bacterial flora caused by antibiotic therapy - Efficacy of multidrug-resistant Lactobacillus preparation on variation of intestinal bacterial flora caused by antibiotic therapy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021718

Enrollment

Registered

2016-05-02

Start date

2016-07-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthopedic disease

Interventions

Administration of multidrug-resistant lactobacillus preparation Control

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who will undergo surgery in the Department of Orthopedic Surgery

Exclusion criteria

Exclusion criteria: 1. Allergy for Lactobacillus preparation 2. Patients who were treated with antibiotics within one month before hospitalization 3. Patients who were treated with lactobacillus preparation within one month before hospitalization 4. Patients with inflammatory bowel disease. 5. Pregnancy 6. for whom the attending doctor considerd he or she is not appropriate for the study.

Design outcomes

Primary

Measure	Time frame
A variety of intestinal bacterial flora	—

Secondary

Measure	Time frame
Digestive symptom, property of stool, stool frequency, and postoperative complication	—

Countries

Japan

Contacts

Public ContactNorihito Kaku

Nagasaki University Hospital Department of Laboratory Medicine

kaku-ngs@umin.ac.jp095-819-7574

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026