Healthy adults
Conditions
Interventions
Ingest 120 mg bilberry extract supplements per day for 6 weeks
Ingest placebo supplements for 6 weeks
Sponsors
ORTHOMEDICO, Inc.
Seishin-kai Medical Association Inc, Takara Medical Clinic.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Healthy Japanese adults 2. Persons who are aware of visual fatigue 3. Persons who usually play TV games, use PC, use Smartphone, or perform VDT for more than 4 hours a day. 4. Persons who corrected visual acuity in both eyes is >= 1.0, and who do not wear contact lenses or switch to glasses from contact lenses during the study.
Exclusion criteria
Exclusion criteria: 1. Persons who have previous medical history of malignant tumor, heart failure or myocardial infarction 2. Patients who are currently under the treatment for either atrial fibrillation, cardiac arrhythmia, hepatic disorder, renal disorder, cerebrovascular disorder, rheumatism, diabetes mellitus, dyslipidemia, hypertension or other chronic diseases 3. Patients who were diagnosed as presbyopia or are aware of presbyopia 4. Patients who have eye disease such as entropion or trichiasis 5. Patients who have uncorrected refractive errors 6. Patients who have severe astigmatism 7. Patients who have cause of visual fatigue except regulatory function such as nerve function, etc. 8. Persons who usually take pharmaceuticals (include herbal medicine), health-promoting diet and health food for the purpose of health maintenance 9. Persons who are allergic to medicines or foods related to the test food of this trial 10. Persons who are pregnant, lactating, or planning to get pregnant during the trial period 11. Persons who were enrolled into other clinical trials within the last 3 months before agreeing to participate in this trial 12. Persons who are judged unsuitable for participating in this trial by physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Miosis frequency (at 0 week and 6 weeks after) * Perform the test before and after VDT for 60 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Flicker test (at 0 week and 6 weeks after) * Perform the test before and after VDT for 60 minutes 2. Subjective symptoms (at 0 week and 6 weeks after) * Perform the test before and after VDT for 60 minutes 3. Schirmer's test (at 0 week and 6 weeks after) | — |
Countries
Japan
Contacts
Public ContactNaoko SUZUKI
ORTHOMEDICO, Inc. R&D Department
Outcome results
None listed