Bone and soft tissue tumor
Conditions
Interventions
Carbon-ion radiotherapy A total of 70.4 GyE consisting of 16 fractions
4.4 GyE /day for 6 or 8 times for 2 weeks
Sponsors
Kanagawa Cancer Center, Kanagawa Prefectural Hospital Organization
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Pathologically diagnosed as primary bone and soft tissue sarcomas 2) Inoperative patient (a) Diagnosed as inoperative tumor by specialized surgeons (b) Refused by patient 3) Patient with measurable tumor 4) 16 years or older and 80 years or younger of age at registration of clinical trial 5) 0 to 2 of ECOG performance status 6) Patient without remote metastasis 7) 6 months or longer of expected survival 8) Informed consent given with document
Exclusion criteria
Exclusion criteria: 1) Primary cranial tumor 2) Past history of radiotherapy for the target lesion 3) Ongoing chemotherapy or within 2 weeks after completion of the chemotherapy 4) Patient with active double cancer 5) Patient with active and intractable infection in the target lesion 6) Patient with artifacts which influence the calculation of irradiation dose 7) Other medical or psychological condition which is unsuitable for carbon-ion therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Local control rate at 2 years | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Overall survival 2) Progression free survival 3) Adverse event rate 4) Quality of life | — |
Countries
Japan
Contacts
Public ContactHiroyuki Katoh
Kanagawa Cancer Center, Kanagawa Prefectural Hospital Organization Ion-beam Radiation Oncology Center
Outcome results
None listed