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Generation of induced pluripotent stem cells (iPSCs) derived from intractable retinal disease patients and clarification of the diseases and novel therapies development by using retinal tissues differentiated and induced from iPSC.

Generation of induced pluripotent stem cells (iPSCs) derived from intractable retinal disease patients and clarification of the diseases and novel therapies development by using retinal tissues differentiated and induced from iPSC. - Generation of induced pluripotent stem cells (iPSCs) derived from intractable retinal disease patients and clarification of the diseases and novel therapies development by using retinal tissues differentiated and induced from iPSC.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000021556
Enrollment
20
Registered
2016-03-22
Start date
2016-04-27
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intractable retinal diseases

Interventions

None listed

Sponsors

Laboretory for Retinal Regeneration Riken Center for Developmental Biology
Lead Sponsor
Department of Ophthalmology Tohoku University Graduate School of Medicine
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Intractable retinal diseases (glaucoma, optic nerve atrophy, retinal choroidal dystrophy, retinal degeneration disease) 20 years of age or more

Exclusion criteria

Exclusion criteria: Under 20 years of age

Design outcomes

Primary

MeasureTime frame
Comparative analysis between the patients and normal people about the morphology, the function, stress response and drug screening of the retinal cells derived from iPSCs.

Countries

Japan

Contacts

Public ContactWataru Kobayashi

Tohoku University Graduate School of Medicine Department of Ophthalmology

nishiguchi@oph.med.tohoku.ac.jp022-717-7294

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026