Dose-finding study of persimmon leaf extract to assess the suppressive effect on postprandial blood glucose levels in healthy subjects

Dose-finding study of persimmon leaf extract to assess the suppressive effect on postprandial blood glucose levels in healthy subjects - Dose-finding study of persimmon leaf extract to assess the suppressive effect on postprandial blood glucose levels in healthy subjects

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000021471

Enrollment

Registered

2016-03-15

Start date

2016-03-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy adult

Interventions

Test food-1: Low-dose extract (350 mL) and Koshihikari boiled rice(147g) Test food-2: Low-dose extract (350 mL) and Koshihikari boiled rice(147g) Control food: water (350 mL) colored with caramel and

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Body mass index (BMI) = <30. 2.Volunteers with no glucose intolelance in the past yesr. 3.Fasting plasma glucose 70-110mg/dl 4.Volunteers being able to make self-judgent to particupate in this study and giving written informed consent. 5.Volunteers having screening test results judged to be appropriate for this study by investigator.

Exclusion criteria

Exclusion criteria: 1.Volunteers having severe history of the diseases (liver,kidney,hert,blood) judged to be inappropriate for this study. 2.Volunteers received gastrectomy,enterectomy,and gastro-intestinal dedeases,judged to be inappropriate for this study. 3.Volunteers having risk of diabetes mellitus (fasting plasma glucose > = 110mg/dl and HbA1c > = 5.9%). 4.Volunteers rejected participating in this study by chief investigater.

Design outcomes

Primary

Measure	Time frame
Time-dependent changes in postprandial blood glucose levels	—

Secondary

Measure	Time frame
Time-dependent changes in postprandial IAUC and GI	—

Countries

Japan

Contacts

Public ContactNiigata Bio-Research Park, Inc

Niigata Bio-Research Park, Inc Business promotion division

nbrp-food-navi@nbrp.co.jp0250-25-1196

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026